PMS Instruments have been the UK Distributor for Hokanson vascular products for over 20 years. During this time their products have been used in leading edge clinical research in the UK by Universities, Hospital and Pharmaceutical companies.
When we first started selling their products the majority of our sales were for applications that used Strain Gauge Plethysmography using Mercury (now Indium Gallium) strain gauges for arterial inflow studies. This concept was invented by Hokanson, is unique and has become well accepted as an industry standard technique.
Two Hokanson products the E20 rapid cuff inflator and AG101 air source were originally used as part of the setup for Strain Gauge Plethysmography. They have now become popular in their own right in the areas of Clinical Pharmacology, Sports Medicine and Sports and Exercise Physiology.
The combination of the Hokanson E20 rapid cuff inflator and AG101 air source can help improve duplex scanning for Venous Reflux and Venous Insufficiency tests.
Rather than manually inflating cuffs which is time consuming and can be uncomfortable for the operator the Hokanson E20 has several advantages:
- It eliminates squatting to squeeze the patient’s leg.
- It compresses all of the soft tissue
- It holds pressure for precisely the correct amount of time
- It rapidly releases the pressure while the leg is duplex scanned for venous reflux
- There is no need for a second person to do the compression
The E20 inflates any cuff in 0.3 sec, holds the pressure indefinitely or for whatever time your protocol needs and then instantaneously deflates the cuff. It works every time no matter the size of the cuff or limb. Simply dial in the pressure needed and push the button for inflation and then push the button to deflate. An optional foot switch and cycle timer is also available.
The combination of the Hokanson E20 rapid cuff inflator and AG101 air source and ease of use mean that brachial artery endothelial function can be measured using the flow-mediated dilation (FMD) technique. The technique still requires skill but is much more reliable and reproducible solution for instant cuff inflation/deflation.
For more information on FMD and Hokanson this recent clinical paper is a good reference
Do acute effects of exercise on vascular function predict adaptation to training? Dawson, E.A., Cable, N.T., Green, D.J. et al. Eur J Appl Physiol (2018) 118: 523. https://doi.org/10.1007/s00421-017-3724-8
In this study the arm was extended and positioned at an angle of ~ 80° from the torso. A forearm cuff was rapidly inflated and deflated using the Hokanson E20 to provide a stimulus to forearm ischemia.
After 20 years it’s great to see Hokanson equipment still being used for new clinical and research applications in the UK.